androgen antagonists การใช้

• Paraben esters, such as butylparaben, have been found to mimic androgen antagonist activity.
• Seviteronel is a non-steroidal antiandrogen, acting specifically as an androgen antagonist of the androgen receptor.
• Oncology products include Velcade ( bortezomib ), for the treatment of multiple myeloma and mantle cell lymphoma and Zytiga ( abiraterone ), an androgen antagonist for the treatment of prostate cancer.
• The compound N-butylbenzene-sulfonamide ( NBBS ) isolated from the bark of " Prunus africana ", the Subsaharan red stinkwood tree, is a specific androgen antagonist and has been used as alternative medicine in benign prostatic hyperplasia.
• "' Antiandrogens "', also known as "'androgen antagonists "'or "'testosterone blockers "', are a class of drugs which prevent androgens like testosterone and dihydrotestosterone ( DHT ) from mediating their biological effects in the body.
• "' Andarine "'( "'GTx-007 "', "'S-4 "') is an investigational selective androgen receptor modulator ( SARM ) developed by GTX, Inc for treatment of conditions such as muscle wasting, osteoporosis and benign prostatic hypertrophy, using the non-steroidal androgen antagonist bicalutamide as a lead compound.